Research highlights

2022

Early introduction of plant polysaccharides drives the establishment of rabbit gut bacterial ecosystems and the acquisition of microbial functions

sleepy rabbit in the nest

The timing of solid food introduction and plant polysaccharides ingestion are two different tools to modulate microbiota implantation and functionality. In mammals, the introduction of solid food is pivotal for the establishment of the gut microbiota. However, the effects of the first food consumed on long-term microbiota trajectory and host response are still largely unknown.

2021

FROGS: a software for easy analysis of metabarcoding data

Microbial communities play a major role in various environmental processes, including carbon recycling and health. The engineering of these ecosystems is largely based on the control of their diversity. FROGS is a user-friendly pipeline dedicated to biologists that gives access to specific diversity of microbial communities from high-throughput sequencing of amplicons. FROGS has been developed to be very fast even on large amounts of data in using cutting-edge tools and an optimized design.

Better understanding of the links between ruminal microbiota and milk production in ewes

Ruminants are able to digest the dietary fibres present in their feed thanks to the micro-organisms - particularly bacteria - present in their fore-stomach (rumen). The relationship between the composition of this ruminal microbiota and various traits of interest, such as feed efficiency, milk composition and animal health, has been established in cattle. Researchers from the GesPR and NED teams of GenPhySE laboratory have studied these relationships in dairy sheep.

2020

Gut microbiota derived metabolites contribute to intestinal barrier maturation at the suckling-to-weaning transition

pig intestine organoid (©Martin Beaumont)

The metabolites produced by the microbiota at the onset of solid food ingestion contribute to the maturation of the gut barrier at the suckling-to-weaning transition. Targeting the gut microbiota metabolic activity during this key developmental window might therefore be a promising strategy to promote intestinal homeostasis.