Comparative genomics reveals insights into avian genome evolution and adaptation.

TitleComparative genomics reveals insights into avian genome evolution and adaptation.
Publication TypeJournal Article
Year of Publication2014
AuthorsZhang, G, Li, C, Li, Q, Li, B, Larkin, DM, Lee, C, Storz, JF, Antunes, A, Greenwold, MJ, Meredith, RW, Ödeen, A, Cui, J, Zhou, Q, Xu, L, Pan, H, Wang, Z, Jin, L, Zhang, P, Hu, H, Yang, W, Hu, J, Xiao, J, Yang, Z, Liu, Y, Xie, Q, Yu, H, Lian, J, Wen, P, Zhang, F, Li, H, Zeng, Y, Xiong, Z, Liu, S, Zhou, L, Huang, Z, An, N, Wang, J, Zheng, Q, Xiong, Y, Wang, G, Wang, B, Wang, J, Fan, Y, da Fonseca, RR, Alfaro-Núñez, A, Schubert, M, Orlando, L, Mourier, T, Howard, JT, Ganapathy, G, Pfenning, A, Whitney, O, Rivas, MV, Hara, E, Smith, J, Farré, M, Narayan, J, Slavov, G, Romanov, MN, Borges, R, Machado, JPaulo, Khan, I, Springer, MS, Gatesy, J, Hoffmann, FG, Opazo, JC, Håstad, O, Sawyer, RH, Kim, H, Kim, K-W, Kim, HJeong, Cho, S, Li, N, Huang, Y, Bruford, MW, Zhan, X, Dixon, A, Bertelsen, MF, Derryberry, E, Warren, W, Wilson, RK, Li, S, Ray, DA, Green, RE, O'Brien, SJ, Griffin, D, Johnson, WE, Haussler, D, Ryder, OA, Willerslev, E, Graves, GR, Alström, P, Fjeldså, J, Mindell, DP, Edwards, SV, Braun, EL, Rahbek, C, Burt, DW, Houde, P, Zhang, Y, Yang, H, Wang, J, Jarvis, ED, M Gilbert, TP, Wang, J
Corporate AuthorsAvian Genome Consortium
JournalScience
Volume346
Issue6215
Pagination1311-20
Date Published2014 Dec 12
ISSN1095-9203
KeywordsAdaptation, Physiological, Animals, Biodiversity, Biological Evolution, Birds, Conserved Sequence, Diet, Evolution, Molecular, Female, Flight, Animal, Genes, Genetic Variation, Genome, Genomics, Male, Molecular Sequence Annotation, Phylogeny, Reproduction, Selection, Genetic, Sequence Analysis, DNA, Synteny, Vision, Ocular, Vocalization, Animal
Abstract

Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades. The avian genome is principally characterized by its constrained size, which predominantly arose because of lineage-specific erosion of repetitive elements, large segmental deletions, and gene loss. Avian genomes furthermore show a remarkably high degree of evolutionary stasis at the levels of nucleotide sequence, gene synteny, and chromosomal structure. Despite this pattern of conservation, we detected many non-neutral evolutionary changes in protein-coding genes and noncoding regions. These analyses reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits.

DOI10.1126/science.1251385
Alternate JournalScience
PubMed ID25504712
PubMed Central IDPMC4390078
Grant ListDP1 OD000448 / OD / NIH HHS / United States
DP1OD000448 / OD / NIH HHS / United States
R01 HL087216 / HL / NHLBI NIH HHS / United States
/ / Howard Hughes Medical Institute / United States