Genomic Prediction Methods Accounting for Nonadditive Genetic Effects.

TitleGenomic Prediction Methods Accounting for Nonadditive Genetic Effects.
Publication TypeJournal Article
Year of Publication2022
AuthorsVarona, L, Legarra, A, Toro, MA, Vitezica, ZG
JournalMethods Mol Biol
Date Published2022
KeywordsAnimals, Genome, Genomics, Genotype, Hybridization, Genetic, Models, Genetic, Phenotype, Selection, Genetic

The use of genomic information for prediction of future phenotypes or breeding values for the candidates to selection has become a standard over the last decade. However, most procedures for genomic prediction only consider the additive (or substitution) effects associated with polymorphic markers. Nevertheless, the implementation of models that consider nonadditive genetic variation may be interesting because they (1) may increase the ability of prediction, (2) can be used to define mate allocation procedures in plant and animal breeding schemes, and (3) can be used to benefit from nonadditive genetic variation in crossbreeding or purebred breeding schemes. This study reviews the available methods for incorporating nonadditive effects into genomic prediction procedures and their potential applications in predicting future phenotypic performance, mate allocation, and crossbred and purebred selection. Finally, a brief outline of some future research lines is also proposed.

Alternate JournalMethods Mol Biol
PubMed ID35451778