Title | Whole-genome resequencing of honeybee drones to detect genomic selection in a population managed for royal jelly. |
Publication Type | Journal Article |
Year of Publication | 2016 |
Authors | Wragg, D, Marti-Marimon, M, Basso, B, Bidanel, J-P, Labarthe, E, Bouchez, O, Le Conte, Y, Vignal, A |
Journal | Sci Rep |
Volume | 6 |
Pagination | 27168 |
Date Published | 2016 |
ISSN | 2045-2322 |
Abstract | Four main evolutionary lineages of A. mellifera have been described including eastern Europe (C) and western and northern Europe (M). Many apiculturists prefer bees from the C lineage due to their docility and high productivity. In France, the routine importation of bees from the C lineage has resulted in the widespread admixture of bees from the M lineage. The haplodiploid nature of the honeybee Apis mellifera, and its small genome size, permits affordable and extensive genomics studies. As a pilot study of a larger project to characterise French honeybee populations, we sequenced 60 drones sampled from two commercial populations managed for the production of honey and royal jelly. Results indicate a C lineage origin, whilst mitochondrial analysis suggests two drones originated from the O lineage. Analysis of heterozygous SNPs identified potential copy number variants near to genes encoding odorant binding proteins and several cytochrome P450 genes. Signatures of selection were detected using the hapFLK haplotype-based method, revealing several regions under putative selection for royal jelly production. The framework developed during this study will be applied to a broader sampling regime, allowing the genetic diversity of French honeybees to be characterised in detail. |
DOI | 10.1038/srep27168 |
Alternate Journal | Sci Rep |
PubMed ID | 27255426 |
PubMed Central ID | PMC4891733 |
Whole-genome resequencing of honeybee drones to detect genomic selection in a population managed for royal jelly.
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