Title | Functional SNP panel for parentage assessment and assignment in worldwide goat breeds. |
Publication Type | Journal Article |
Year of Publication | 2018 |
Authors | Talenti, A, Palhière, I, Tortereau, F, Pagnacco, G, Stella, A, Nicolazzi, EL, Crepaldi, P, Tosser-Klopp, G |
Corporate Authors | AdaptMap consortium |
Journal | Genet Sel Evol |
Volume | 50 |
Issue | 1 |
Pagination | 55 |
Date Published | 2018 Nov 19 |
ISSN | 1297-9686 |
Abstract | BACKGROUND: International standard panels of single nucleotide polymorphisms (SNPs) have replaced microsatellites in several species for parentage assessment and assignment (PA) purposes. However, such a resource is still lacking in goats. The application of a cheap tool for PA would help the management of goat populations by improving the reliability of pedigree registration and, consequently, allow a better implementation of breeding schemes or conservation programs.RESULTS: Using data from the current GoatSNP50 chip, starting from a worldwide dataset of more than 4000 animals belonging to more than 140 breeds and populations from the AdaptMap initiative, we selected a panel of 195 SNPs. The assignment rate of this panel was up to 100% on an additional dataset that included 2000 Alpine and Saanen animals and highly related candidate sires.CONCLUSIONS: In this study, we defined a highly informative SNP panel, which will be publicly available to worldwide breeders and laboratories. Its development on such a large number of breeds and populations, together with validation on a second set of cosmopolitan breeds, makes it a promising and important genomic tool for the goat species. |
DOI | 10.1186/s12711-018-0423-9 |
Alternate Journal | Genet. Sel. Evol. |
PubMed ID | 30449282 |
PubMed Central ID | PMC6240953 |
Grant List | 245140 / / 3SR Sustainable Solutions for Small Ruminants / |
Functional SNP panel for parentage assessment and assignment in worldwide goat breeds.
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