Intraindividual Variation of Meiotic Recombination Parameters in Pig Spermatocytes: A Preliminary Study.

TitleIntraindividual Variation of Meiotic Recombination Parameters in Pig Spermatocytes: A Preliminary Study.
Publication TypeJournal Article
Year of Publication2018
AuthorsMary, N, Ferchaud, S, Barasc, H, Calgaro, A, Bonnet, N, Ducos, A, Pinton, A
JournalCytogenet Genome Res
Volume154
Issue4
Pagination229-233
Date Published2018
ISSN1424-859X
KeywordsAnimals, Biological Variation, Individual, Genetic Variation, Male, Meiosis, MutL Protein Homolog 1, Pachytene Stage, Recombination, Genetic, Spermatocytes, Swine
Abstract

Meiotic recombination parameters like crossover (CO) rate or synaptonemal complex (SC) length are known to vary strongly between individuals and between cells from the same individual. The origins of this variability remain elusive, and little is known about the variations that might occur between different samples and/or over time within the same individual. To document this question, pachytene cells from 3 boars of the Large White breed were analyzed twice, at a 1-year interval, using immunocytological techniques. CO rate, SC length, and MLH1 inter-foci distances varied significantly between the 3 individuals. CO rate and SC length differed significantly between the 2 sampling periods for 1 individual. However, no significant differences were observed between the 2 samples for CO distribution and inter-foci distances in the 3 boars studied.

DOI10.1159/000488789
Alternate JournalCytogenet. Genome Res.
PubMed ID29788002