I am interested in the development of inference methods for population genetics, and in their application to farm animal species.
The methods I develop aim at reconstructing the evolution history of species, based on genomic data observed in these species.
They concern both neutral (population size history, population structure ...)
and adaptive (detection of locus under selection, estimation of selection history ...) aspects of this evolution.
I apply these methods to a wide range of plant and animal species,
mostly farm animal species (cattle and sheep essentially) for which I try to decipher the domestication process and the consequences of recent intensive selection.
Phone:
0561285117
Publications
Genome-Wide Analysis of the World’s Sheep Breeds Reveals High Levels of Historic Mixture and Strong Recent Selection. PLoS Biol 10, e1001258 (2012).
Genome-wide linkage disequilibrium in the Blonde d’Aquitaine cattle breed. Journal of Animal Breeding and Genetics n/a–n/a (2012). doi:10.1111/j.1439-0388.2012.01020.x
Genetic characterization of the Blonde d’Aquitaine cattle breed using microsatellite markers and relationship with three other French cattle populations. Journal of animal breeding and genetics 128, 201-8 (2011).
Epilepsy caused by an abnormal alternative splicing with dosage effect of the SV2A gene in a chicken model. PloS one 6, e26932 (2011).
Sparse PLS discriminant analysis: biologically relevant feature selection and graphical displays for multiclass problems. BMC bioinformatics 12, 253 (2011).