I am interested in the development of inference methods for population genetics, and in their application to farm animal species.
The methods I develop aim at reconstructing the evolution history of species, based on genomic data observed in these species.
They concern both neutral (population size history, population structure ...)
and adaptive (detection of locus under selection, estimation of selection history ...) aspects of this evolution.
I apply these methods to a wide range of plant and animal species,
mostly farm animal species (cattle and sheep essentially) for which I try to decipher the domestication process and the consequences of recent intensive selection.
Phone:
0561285117
Publications
Functional investigation of a QTL affecting resistance to Haemonchus contortus in sheep. Vet Res 45, 68 (2014).
Detecting Signatures of Selection Through Haplotype Differentiation Among Hierarchically Structured Populations. Genetics (2013). doi:10.1534/genetics.112.147231
Pool-hmm: a Python program for estimating the allele frequency spectrum and detecting selective sweeps from next generation sequencing of pooled samples. Molecular Ecology Resources n/a–n/a (2013). doi:10.1111/1755-0998.12063
Detection of signatures of selective sweeps in the Blonde d'Aquitaine cattle breed. Anim Genet 44, 579-83 (2013).
Detecting selective sweeps from pooled next-generation sequencing samples. Molecular biology and evolution 29, 2177-86 (2012).